Jianbin Yan
Researcher
Deputy Dean of Agricultural Synthetic Biology Center, AGIS
Ph.D., Tsinghua University, 2010
Keywords: synthetic biology, multi-omics big data, molecular biology, chemical biology, genetics
Email: [email protected]
Research Interest
Plant secondary metabolites have a variety of biological activities, are widely used in multiple fields including medicine, agriculture, food, and ecology. Phytohormone jasmonate is responsible for the regulation of defense response by an accumulation of secondary metabolites. Our team comprehensively uses synthetic biology, multi-omics big data, molecular biology, chemical biology, and genetics to elucidate regulatory mechanisms of the jasmonate signaling pathway to plant secondary metabolism. The study is closely related to crop quality identification and the artificial design of plant metabolism exploring novel breeding strategies.
Selected Publications
1.	Xiong X#, Gou J#, Liao Q#, Li Y#, Zhou Q, Bi G, Li C, Du R, Wang X, Sun T, Guo L, Liang H, Lu P, Wu Y, Zhang Z, Ro D-K, Shang Y, Huang S*, Yan J* (2021) The Taxus genome provides insights into paclitaxel biosynthesis. Nature Plants, doi: 10.1038/s41477-021-00963-5. (CAS Biology Division Top 1, JCR Q1)
2.	Du R#, Li C#, Pan P, Lin C S K, Yan J* (2021) Characterization and evaluation of a natural derived bacterial consortium for efficient lignocellulose, Bioresource Technology, 329: 124909. (CAS Engineering Division Top 1, JCR Q1)
3.	Li C#, Ong K L, Cui Z, Sang Z, Li X, Patria R D, Qi Q, Fickers P, Yan J*, Lin C* (2021) Promising advancement in fermentative succinic acid production by yeast hosts. Journal of Hazardous Materials, 401: 123414. (CAS Environmental Science and Ecology Division Top 1, JCR Q1)
4.	Yang X#, Yan J#, Zhang Z#, Lin T, Xin T, Wang B, Wang S, Zhao J, Zhang Z, Lucas W, Li G, Huang S* (2020) Regulation of plant architecture by a novel histone acetyltransferase targeting gene bodies, Nature Plants, 6(7): 809-822. (CAS Biology Division Top 1, JCR Q1)
5.	Yang M#, Yan C#, Griffith M, Zhao J, Zhang Y, Xie D, Yan J* (2020) Arabidopsis EED1 encoding a plant-specific nuclear protein is essential for early embryogenesis, Journal of Genetics and Genomics, 47(1): 61-64. (CAS Biology Division Top 1, JCR Q1)
6.	Liao Q#, Du R#, Gou J, Guo L, Shen H, Liu H, Nguyen J, Ray M, Yin T, Huang S, Yan J* (2020) The genomic architecture of sex determining region and sex-related metabolic variation in Ginkgo biloba. Plant Journal, 104(5): 1399-1409. (CAS Biology Division Top 1, JCR Q1)
7.	Yan J#, Yao R#, Chen L, Li S, Gu M, Nan F, Xie D* (2018) Dynamic perception of jasmonates by the F-box protein COI1, Molecular Plant, 11(10): 1237-1247. (CAS Biology Division Top 1, JCR Q1, Entered“Research Advances in Plant Science in China in 2018”)
8.	Li H#, Yao R#, Ma S#, Hu S, Li S, Wang Y, Yan C, Xie D*, Yan J* (2017) Efficient ASK-assisted system for expression and purification of plant F-box proteins, Plant Journal, 92(4): 736-743. (CAS Biology Division Top 1, JCR Q1)